Note a lot of this was announced at the Frankfurt Auto Show for the 2010 GS450h, this is just confirmation that similar changes apply to other GS models...
As far as I can remember:
Cons:
Losing cassette deck from sound system
Losing memory buttons for passenger seat
Pros:
Gen 6 NAV with 40GB hard disk, casual voice recognition, still touchscreen not mouse
USB and AUX connection (iPod/iPhone) as standard
XM Radio includes XM Traffic (real-time updates)
Enform etc (OnStar equivalent)
Neutral:
Golden almond and black sapphire colors replaced by ? and Deep Sea Mica (similar colors)
Cashmere interior replaced by something else (parchment?)
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"Очень нравицца Сетка рабица,
Ножом не режица, Ядом не травица,
Пнешь - качаица! Ух, красавица!" (Ц)